Some chemotherapy drugs used to treat cancer, such as vincristine, interfere with the creation of mitotic spindle fibers of a cell. Explain how this drug affects mitosis
What will be an ideal response?
The mitotic spindle is formed during prophase by centrioles. This spindle guides the movement of chromosomes later as mitosis progresses. By late prophase, the spindle has attached to the centromere of each chromosome. Without the creation of the spindle fibers, chromosomes cannot successfully be separated as mitosis progresses through anaphase.
You might also like to view...
A cell's or tissue's response to a hormone primarily depends on ________ and ________.
Fill in the blank(s) with the appropriate word(s).
An axon will depolarize only if the membrane potential reaches between -70mV and -55mV. This follows the ________.
A. all-or-none law B. graduated law C. recruitment law D. threshold law
Merkel cells are pressure-sensitive cells found in which location?
a. Cochlea b. Crista ampullaris c. Epidermis d. Muscle spindles e. Reticular dermis of the skin
Which of the following statements regarding the cardiac cycle is TRUE?
A. The AV valves are open during mid-to-late diastole. B. The aortic valve is open during isovolumetric ventricular contraction. C. The first heart sound is caused by the closing of the semilunar valves. D. The dicrotic notch is a result of closure of the AV valves. E. Closure of the AV valves occurs when the ventricles reach end-systolic volume.