A client is prescribed omeprazole, bismuth subsalicylate, and metronidazole for the treatment of H. pylori. The nurse explains that combination therapy will accomplish which outcome?
1. Increase the number of ulcerations
2. Eliminate the population of H. pylori
3. Allow H. pylori to adhere to the gastric mucosa
4. Immediately relieve symptoms of gastric ulceration
Correct Answer: 2
Rationale 1: A goal of combination therapy is not to increase the number of ulcerations.
Rationale 2: A goal of combination therapy is to eliminate the population of H. pylori.
Rationale 3: Combination therapy will inhibit bacterial growth by disrupting their cell wall and preventing H. pylori from adhering to the gastric mucosa.
Rationale 4: The goal of combination therapy is to eradicate H. pylori and heal ulcerations. Symptoms will not immediately be relieved by this therapy.
Global Rationale: The goal of combination therapy is to eradicate H. pylori and heal ulcerations. Symptoms will not immediately be relieved by this therapy. Combination therapy will inhibit bacterial growth by disrupting their cell wall and preventing H. pylori from adhering to the gastric mucosa.
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