Which of the following terms describes the drug dose that produces 50% of the maximum possible response?
a. effective dose (ED50)
b. lethal dose
c. maximum response
d. half-life (t1?2)
a. Effective dose is the dose that produces 50% of the maximal response. The potency of a drug varies inversely with a drug's ED50 . For example, a drug whose ED50 is 4 mg is ten times more potent than a drug whose ED50 is 40 mg.
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