The nurse checks the margin of safety (MOS) for a drug that will be administered to a client, knowing that the MOS is the amount of drug that is lethal to ____ % of animals divided by the amount that produces a therapeutic effect in ____ % of animals
Fill in the blank with the appropriate word.
Correct Answers: 1, 99
Rationale: The MOS is calculated as the amount of drug that is lethal to 1% of animals (LD1) divided by the amount of drug that produces a therapeutic effect in 99% of the animals (ED99).
Global Rationale: The MOS is calculated as the amount of drug that is lethal to 1% of animals (LD1) divided by the amount of drug that produces a therapeutic effect in 99% of the animals (ED99).
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