You synthesize polyribonucleotides using a molar ratio of 3 Uracil :
1 Guanine. The resulting polyribonucleotide sequences are random but each polyribonucleotide follows the 3:1 ratio. When this mixture of polyribonucleotides is used as template for translation, proteins with different amino acid sequences are obtained. When you determine the amino acids present in the proteins, you obtain the frequencies for each amino reported in the table below. The frequency of phenylalanine was normalized to 1 and all other amino acids are reported as a frequency of occurrence compared to phenylalanine. As an example of understanding the data, the amino acid glycine frequency is 0.12, meaning that glycine was present in the mixture of polypeptides at a ratio of 12 glycine residues (amino acids) for every 100 phenylalanine residues (amino acids).
Amino acid Frequency
Phenylalanine 1.00
Leucine 0.37
Valine 0.36
Cysteine 0.35
Tryptophan 0.14
Glycine 0.12
Which one of the following statements about this experimentis true?
A. The most likely codon present in the polyribonucleotides synthesized under these conditions is GGG.
B. Codons consisting of one guanine and two uracils, in any order, are likely to encode for either valine, leucine, or cysteine.
C. A codon for tryptophan is as likely to be present as is the codon for phenylalanine.
D. Since only poly(G) and poly(U) RNA are present, the presence of valine shows ribosome slippage during translation.
B
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