A client has just been prescribed an antidepressant medication. The client asks, "How long before this gets into my blood so I feel better?" How should the nurse respond?

Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. "The medication will be at the desired level in your blood in 3 to 4 days."
2. "We are not certain how quickly the medication gets into your blood."
3. "Let me worry about that. You just take your medicine as prescribed."
4. "The medication gets into the blood fairly quickly, but it may take weeks for you to feel the full effects."
5. "It is not just the medication getting into your blood that makes you feel better."


1,4,5
Rationale 1: Most antidepressant medications are present in the blood at therapeutic levels in 72 to 96 hours.
Rationale 2: This statement is not true and is not therapeutic.
Rationale 3: This is not a therapeutic response.
Rationale 4: Symptom improvement may be delayed by as much as three to six weeks.
Rationale 5: There are processes as yet unknown that also act to improve symptoms, as evidenced by the lag between therapeutic blood levels and symptom improvement.

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