The core histones are small, basic proteins that have a globular domain at the C-terminus and a long, extended conformation at the N-terminus. Which of the following is not true of the N-terminal "tail" of these histones?

(a) It is subject to covalent modifications.
(b) It extends out of the nucleosome core.
(c) It binds to DNA in a sequence-specific manner.
(d) It helps DNA pack tightly.


(c)

Biology & Microbiology

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In humans, hemophilia is caused by a recessive allele on the X chromosome. Suppose a man with hemophilia has children with a healthy woman whose mother had hemophilia. If an ultrasound test shows that their first child is a girl, what is the probability that she has hemophilia? (Enter the probability as a percent. Enter the number only without the percent sign. For example, enter 100% as 100 and enter 12.5% as 12.5 )  

50 Clarify Question · What is the key concept addressed by the question? · What type of thinking is required? · What key words does the question contain?   Gather Content · What do you already know about X-linked inheritance?   Consider Possibilities · What other information is related to the question? Which information is most useful?   Choose Answer · Given what you now know, what information and/or problem solving approach is most likely to produce the correct answer?   Reflect on Process · Did your problem-solving process lead you to the correct answer? If not, where did the process break down or lead you astray? How can you revise your approach to produce a more desirable result?

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Biology & Microbiology

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Biology & Microbiology