What type of mutation does not change the amino acid sequence and thus has no observable consequence?
a. Frameshift
b. Spontaneous
c. Silent
d. Missense
ANS: C
Silent mutations do not change the amino acid sequence and therefore have no consequences. Frameshift mutations involve the insertion or deletion of one or more base pairs of the DNA molecule. They alter the amino acid sequence. Spontaneous mutations occur in the absence of exposure to a mutagen and produce changes in the amino acid sequence. Missense mutations, a form of base pair substitution, alter amino acids, which produce a change (i.e., the "sense") in a single amino acid.
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