Which automatic hematology analyzer performs the white count (by both optical scatter and electrical impedance) and then compares the two as an internal quality control check?
a. Sysmex 9000/9500
b. Coulter LH750
c. CELL-DYN 4000
d. Advia 2100
ANS: C
The CELL-DYN 4000 performs the white count using optical scatter (WOC) and electrical impedance (WIC). Software compares the two as an internal quality control check. When the WOC and the WIC differ, an algorithm selects the most appropriate value for the reported white cell count. Newborn samples, which contain a high concentration of fetal hemoglobin, are an example of when a discrepancy might exist between the two. The soft lysing agent used in the WOC channel is unable to completely lyse the red cells, raising the WOC count compared with the WIC.
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