What is the difference between coenzymes and cofactors, and where do we get them from?


Cofactors are inorganic substances, or minerals, such as zinc, potassium, iron, and magnesium. Some enzymes require that cofactors be attached to their active sites in order to function. Coenzymes are organic molecules derived from vitamins such as niacin and riboflavin. Unlike cofactors, coenzymes are not actually a part of the enzyme structure. Rather, they assist enzymes by accepting and donating hydrogen ions (H+), electrons (e-), and other molecules during chemical reactions. The vitamins in our diet provide coenzymes and the minerals provide cofactors.

Nutritional Science

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