A patient with chronic myeloid leukemia (CML) begins treatment with imatinib (Gleevec). Which statement by the patient indicates understanding of this medication?
a. "Resistance to this drug may develop over time."
b. "The intensity of side effects is dose dependent."
c. "This drug does not have significant drug interactions."
d. "This drug must be given intravenously."
ANS: A
Over time, resistance to imatinib may develop because the genes that code for BCR-ABL can mutate. Side effects of imatinib are not dose-dependent. Imatinib has significant drug interactions with several drugs. Imatinib is given orally.
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