The karyotype of a person is 47, XY, +21. This person is a:
a. Normal male. c. Normal female.
b. Male with Down syndrome. d. Female with Turner syndrome.
ANS: B
This person is male because his sex chromosomes are XY. He has one extra copy of chromosome 21 (for a total of 47 instead of 46), resulting in Down syndrome. A normal male would have 46 chromosomes. A normal female would have 46 chromosomes and XX for the sex chromosomes. A female with Turner syndrome would have 45 chromosomes; the sex chromosomes would have just one X.
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