A client is prescribed salmeterol (Serevent) by inhalation for asthma. The client asks the nurse how the medication can help. The nurse's response should be based on the fact that salmeterol (Serevent) is which type of agonist?
1. Nonselective adrenergic agonist
2. Selective beta-2 agonist
3. Selective alpha-1 agonist
4. Selective beta-1 agonist
Correct Answer: 2
Rationale 1: Salmeterol (Serevent) is not a nonselective agonist.
Rationale 2: Salmeterol (Serevent) is a selective beta-2 agonist with fewer cardiac side effects and a longer duration of action. Its effects are delayed, but persist for up to 12 hours. Hence it can be used as pharmacotherapy for chronic asthma.
Rationale 3: Salmeterol (Serevent) has no action on alpha-1 receptors.
Rationale 4: Salmeterol (Serevent) has no effect on beta-1 receptors.
Global Rationale: Salmeterol (Serevent) is a selective beta-2 agonist with fewer cardiac side effects and a longer duration of action. Its effects are delayed, but persist for up to 12 hours. Hence it can be used as pharmacotherapy for chronic asthma. Salmeterol (Serevent) is not a nonselective agonist. Salmeterol (Serevent) has no action on alpha-1 receptors or beta-1 receptors.
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