Because MAO inhibitors have long-acting metabolites:
a. at least 2 weeks should elapse between administration of some other antidepressant
b. the half-lives of the medications are likely to be very long as well
c. they have many associated and serious side effects
d. they are the most effective of the antidepressant medications that can be administered
A
At least 2 weeks should elapsed between the administration of MAOIs and the administration of another type of antidepressant. Furthermore, administration of MAOIs should not be discontinued abruptly. Rather, the administration should be stopped gradually to avoid significant side effects.
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