Which statement by a patient about to begin taking orlistat (Xenical) for weight loss therapy indicates an understanding of this drug's actions?
a. "I can eat as much as I want and still lose weight."
b. "I should avoid fat-soluble vitamin supplements while taking this drug."
c. "If I take a bulk-forming laxative, I can reduce the incidence of fecal incontinence."
d. "If I take the drug 4 times daily instead of twice daily, I will lose weight faster."
ANS: C
Because orlistat reduces fat absorption, stools often are fatty or oily, and fecal incontinence can occur. Bulk-forming laxatives can help with this side effect. For orlistat to be effective, patients still need to adopt a reduced-calorie diet with a 30% fat content. Patients should take fat-soluble vitamin supplements to replace those lost in stools. Taking the drug more often does not increase weight loss.
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