A discussion of the future of risk prevention for common disease based on genetics would include which information?

Question

Note: Credit will be given only if all correct choices and no incorrect choices are selected.
Standard Text: Select all that apply.
1. Risk modification could be more specific to populations that share common ancestry.
2. Diseases could be identified at earlier stages because screening recommendations would be more specific.
3. Additional emphasis could be placed on the use of current well-validated risk calculators.
4. Disease prevention could be targeted to individuals.
5. Some current recommendations for risk reduction may be withdrawn for some populations.

Answer 1

1,2,4,5
Rationale 1: Today's recommendations for risk modification are largely generic. If population-specific genetic risks are identified, more specific risk modification interventions could be designed.
Rationale 2: If the risk for developing disorders is identified for specific populations, screening recommendations could be individualized to those populations.
Rationale 3: Genetic testing has not yet demonstrated additional predictive value when added to well-validated risk calculators.
Rationale 4: Better understanding of genetic linkages would affect both treatment and risk reduction for individuals as well as for populations.
Rationale 5: Current recommendations are generic. It may be discovered that some of these standards do not apply to all populations.