Which of the following diets, given to patients with ARDS, reduces the number of ventilator days, ICU days, and the number of days requiring supplemental O2?
A. omega-6 fatty acid-20 diet
B. a 70:30, fat:carbohydrate diet
C. EPA-plus-GLA diet
D. A 20:80, protein:carbohydrate diet
?ANS: C
A. Incorrect response: See explanation C.
B. Incorrect response: See explanation C.
C. Correct response: A specific enteral formula for mechanically ventilated patients with acute respiratory distress syndrome (ARDS) has been introduced. This formula (Oxepa) relies on the use of anti-inflammatory specific fatty acids to modulate the inflammatory response. Fatty acids, such as eicosapentaenoic acid (EPA; omega-3 fatty acid, 20:5n3), have been used successfully to dampen inflammation in several chronic diseases. The clinical benefits observed in patients given EPA plus GLA were a significant reduction in ventilator days and ICU days, and a decrease in supplemental O2 days.
D. Incorrect response: See explanation C.
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