A drug action in which the effects of using two drugs together is greater than the sum of the effects of using each one alone is called

toxicity
synergism
cumulative effect
antagonism
side effect


synergism

Rationale: Synergism is a drug action in which the effects of using two drugs together is greater than the sum of the effects of using each one alone; cumulative effect is described as repeated doses of a drug which may build up or accumulate in the body; a side effect is described as toxic effects or undesirable results other than for which the drug was intended; toxicity is described as harmful effects of a drug; and antagonism is the interaction of two or more drugs, causing a change in the expected effect of each drug.

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