All of the following statements regarding interleukin-2 (IL-2) or its receptor are true except _____
a. The low-affinity IL-2 receptor is a membrane-bound heterodimer composed of ? and ? chains.
b. IL-2 production increases approximately 100-fold if a co-stimulatory signal is delivered.
c. T-cell proliferation occurs upon binding of IL-2 to the high-affinity IL-2 receptor.
d. The high-affinity IL-2 receptor is assembled after T-cell activation.
e. Rapamycin is an immunosuppressive drug that inhibits signaling of IL-2 through the IL-2 receptor.
A
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