A nursing instructor is preparing a class on various antibacterial drugs interfering with protein synthesis, with the discussion focusing on quinupristin/dalfopristin
Which of the following medications would the instructor include as interacting with quinupristin/dalfopristin, thus increasing the risk for toxicity? Select all that apply.
A) Lorazepam (Ativan)
B) Quinapril (Accupril)
C) Ritonavir (Norvir)
D) Atorvastatin (Lipitor)
E) Tacrolimus (Prograf)
Ans: A, C, D
Feedback:
When quinupristin/dalfopristin is prescribed, it may interact with the following drugs, increasing serum levels and thus the risk for toxicity: antiretrovirals, antineoplastic and immunosuppressant agents, calcium channel blockers, benzodiazepines, and cisapride.
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