Which theory of etiology of Alzheimer's disease, suggested by current research, might the nurse use to help a family understand that this disorder is not of psychosocial origin? Alzheimer's dis-ease is associated with:
1. ?-amyloid protein deposits in the brain
2. Abnormal serotonin reuptake
3. Excessive acetylcholine in the frontal cortex
4. Prion infection of gray matter
ANS: 1
The prevailing theories of etiology of Alzheimer's disease include the following: angiopathy and blood-brain barrier incompetence; neurotransmitter and receptor deficiencies of acetylcholine; abnormal proteins, specifically ?-amyloid and their products; and genetic defects. Neither sero-tonin nor prions are implicated as problems in Alzheimer's disease.
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