A patient is admitted to the hospital and will begin taking levothyroxine (Synthroid). The nurse learns that the patient also takes warfarin (Coumadin). The nurse will notify the provider to discuss _____ the _____ dose
a. reducing; levothyroxine
b. reducing; warfarin
c. increasing; levothyroxine
d. increasing; warfarin
ANS: B
Levothyroxine accelerates the degradation of vitamin K–dependent clotting factors, which enhances the effects of warfarin. Patients taking warfarin who start taking levothyroxine may need to have their warfarin dose reduced. It is not correct to increase or decrease the levothyroxine dose or to increase the warfarin dose.
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