The patient receives morphine for pain. He asks the nurse how it works to relieve pain. What is the best response by the nurse?
1. "It inhibits the primary pain neurotransmitters in your brain."
2. "It stimulates the receptors that secrete endorphins in your brain."
3. "It interacts with receptors in your body that produce analgesia."
4. "It promotes the primary pleasure neurotransmitters in your brain."
3
Rationale 1: Opioids do not inhibit neurotransmitters responsible for pain.
Rationale 2: Opioids do not promote secretion of endorphins.
Rationale 3: Opioids exert their actions by interacting with the mu and kappa receptors in the brain. Drugs that stimulate these receptors are opioid agonists.
Rationale 4: Opioids do not promote release of the pleasurable neurotransmitters. Opioids do not promote secretion of endorphins.
Global Rationale: Opioids exert their actions by interacting with the mu and kappa receptors in the brain. Drugs that stimulate these receptors are opioid agonists. Opioids do not promote release of the pleasurable neurotransmitters. Opioids do not promote secretion of endorphins. Opioids do not inhibit neurotransmitters responsible for pain.
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