What would be the expected response if a person had less than the normal amount of bicarbonate in the blood and other extracellular fluids?
A. The person would be at increased risk for acidosis.
B. The person would be at decreased risk for acidosis.
C. The person would be at increased risk for alkalosis.
D. The person would be at decreased risk for alkalosis.
A
Bicarbonate (H2CO3–) is a weak base with an overall negative charge. When hydrogen ions are present in a slight or mild excess (mild acidosis), bicarbonate can buffer or absorb the excess hy-drogen ions, reducing the hydrogen ion concentration and bringing the pH back up to normal. If the total body bicarbonate concentration is low, especially in the blood, the action of buffering or absorbing excess hydrogen ions is reduced, and the person is at increased risk for acidosis.
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