The nurse is conducting family planning with a healthy couple. The man's father had cystic fibrosis and his mother was healthy with no family history of the condition. The woman's family has no history of cystic fibrosis. Which is the most appropriate response for the nurse to make when asked about the risk of their child having cystic fibrosis?
A) All children will have cystic fibrosis.
B) Each child has a 50% chance of cystic fibrosis.
C) Each child has a 50% chance of being a carrier for cystic fibrosis.
D) All children will be carriers for cystic fibrosis.
C) Each child has a 50% chance of being a carrier for cystic fibrosis.
Explanation: A) Because it is a recessive disorder, an affected individual must inherit one defective cystic fibrosis gene from each parent for the disease to be expressed. In this couple, the man's father must have had two recessive genes in order to develop the condition, and his son (the man in this couple) would be a carrier. The woman in this couple has no genes for cystic fibrosis. In this scenario, each child has a 50% chance of carrying the gene (being a carrier). No children will develop cystic fibrosis.
B) Because it is a recessive disorder, an affected individual must inherit one defective cystic fibrosis gene from each parent for the disease to be expressed. In this couple, the man's father must have had two recessive genes in order to develop the condition, and his son (the man in this couple) would be a carrier. The woman in this couple has no genes for cystic fibrosis. In this scenario, each child has a 50% chance of carrying the gene (being a carrier). No children will develop cystic fibrosis.
C) Because it is a recessive disorder, an affected individual must inherit one defective cystic fibrosis gene from each parent for the disease to be expressed. In this couple, the man's father must have had two recessive genes in order to develop the condition, and his son (the man in this couple) would be a carrier. The woman in this couple has no genes for cystic fibrosis. In this scenario, each child has a 50% chance of carrying the gene (being a carrier). No children will develop cystic fibrosis.
D) Because it is a recessive disorder, an affected individual must inherit one defective cystic fibrosis gene from each parent for the disease to be expressed. In this couple, the man's father must have had two recessive genes in order to develop the condition, and his son (the man in this couple) would be a carrier. The woman in this couple has no genes for cystic fibrosis. In this scenario, each child has a 50% chance of carrying the gene (being a carrier). No children will develop cystic fibrosis.
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