Long-term depression (LTD) is due to which of the following?
A. Conversion of silent synapses to active synapses
B. Removal of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors from the postsynaptic membrane
C. Addition of dopamine receptors to the presynaptic membrane
D. Pairing of presynaptic and postsynaptic firing
ANS: B
Rationale: LTD is the conversion of an active synapse to a silent synapse by the removal of AMPA receptors from the membrane into the cytoplasm.
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