Which drug is the cornerstone of treatment for prophylaxis and treatment of tuberculosis (TB)?
a. Amphotericin B (Abelcet)
b. Streptomycin (Streptomycin)
c. Isoniazid (Nydrazid)
d. Acyclovir (Zovirax)
ANS: C
Isoniazid has been the mainstay for years in the treatment and prevention of TB. The mechanism of action of isoniazid is not fully known. Isoniazid appears to disrupt the Mycobacterium tuberculosis cell wall and inhibit replication. Amphotericin B is used in the treatment of fungal infections. Streptomycin is an aminoglycoside used to treat bacterial infections. Acyclovir is used in the treatment of viral infections associated with herpes simplex virus.
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