Traditional therapy in APL includes pharmacological concentration of retinoic acid (ATRA) and chemotherapy. What is the function of the chemotherapy component in this treatment protocol?

a. Induces maturation of the promyelocytes to mature granulocytes
b. Binds with the target PML/RARA gene and represses gene transcription
c. Eradicates the leukemic stem cells
d. Induces cytolysis of the malignant promyelocytes


Correct Answer: C

Health Professions

You might also like to view...

________ EHR uses electronic signatures to identify who entered each piece of information into the patient's chart

Indicate whether the statement is true or false

Health Professions

________ Many medical offices contract an independent payroll company

Indicate whether the statement is true or false

Health Professions

Determining whether services provided to a patient are appropriate for the patient's current or proposed level of care is called __________

a. case mix management b. intensity of services c. severity of illness d. value-based purchasing

Health Professions

Medicare's architects created a tension between Medicare's short-term goals and its long-term aspirations. What were the long-term aspirations?

A) expanding Medicare into national health insurance B) organizing physicians into managed care groups C) providing low-cost health care to the poor D) adopting a resource-based relative value scale

Health Professions