Hemoglobin C disease has altered solubility properties similar to hemoglobin S disease. What accounts for this altered solubility?
a. Heme iron is in the ferric form rather than ferrous form.
b. The hemoglobin remains in the tense structure.
c. A nonpolar amino acid is substituted for a polar amino acid.
d. A polar amino acid is substituted near the pocket where heme binds.
Correct Answer: C
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