Calculate the approximate PAO2 given the following conditions (assume R = 0.8): FiO2 = .40, PB = 770 mm Hg, PACO2 = 31 mm Hg
a. 100 mm Hg
b. 135 mm Hg
c. 250 mm Hg
d. 723 mm Hg
ANS: C
PAO2 = FiO2 ? (PB – 47) – PACO2 ÷ 0.8
where FiO2 is fraction of inspired oxygen, PB is barometric pressure, 47 is water vapor tension (in mm Hg) at 37° C, PACO2 is alveolar PCO2, and 0.8 is normal respiratory exchange ratio (R).
PAO2 = 0.4(770 – 47) – (31/0.8)
PAO2 = 250.45 mm Hg
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