X chromosome inactivation is caused by the accumulation of:
A. proteins produced by the Xist gene; these
proteins induce methylation, histone
modification, and other changes associated
with preventing transcription.
B. coding RNA produced by the Xist gene;
this RNA, in addition to coding for Xist
proteins, binds to and coats the X
chromosome undergoing inactivation and
physically prevents it from being transcribed.
C. non-coding RNA produced by the Xist
gene, which coats the X chromosome and
physically prevents it from being unwound,
"unzipped," and transcribed.
D. non-coding RNA produced by the Xist
gene, which coats the X chromosome and
induces methylation, histone modification,
and other changes associated with
preventing transcription.
E. None of these choices accurately describe
the process of X chromosome inactivation.
D
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