A tumor suppressor gene is cloned and mutagenized in vitro, then injected into mouse embryos to create knockout mice. How could you identify the heterozygous knockout mice and create mice susceptible to tumors?
What will be an ideal response?
Reared heterozygous mice can be screened molecularly to identify the ones with the mutation. Interbreeding these mice will result in some homozygous knockout progeny, which in turn will show rapid development of tumors.
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List the four essential components of cell communication and provide their functions
What will be an ideal response?
Which of the following events do not occur in non-stop mRNA decay?
A. A string of lysine residues are added at the C-terminus of the polypeptide. B. The stalled ribosome recruits Ski7 protein. C. Ski7 protein degrades the defective protein by recognizing the C-terminal poly(Lys) tag. D. An exosome ribonuclease degrades the mRNA.
Monosaccharides and disaccharides are types of ____
a. proteins b. lipids c. nucleic acids d. carbohydrates e. amino acids
Disruptive selection favors
a. the intermediate forms. b. an extreme at one end of a range of variation. c. the extremes at both ends of a range of variation. d. a greater number of individuals in the center of the bell-shaped curve. e. neutral traits.