A patient was suspected of having a rickettsial infection after hiking in the Rocky Mountains. A Weil-Felix test was performed, which resulted in no agglutination observed. Which one of the following statements explains this discrepancy?

a. Detection of rickettsial infections using strains of Proteus is not as specific as other serologic tests; therefore the infec-tions should be retested with a newer me-thod.
b. The Weil-Felix test is not the appropriate test to order; it cannot detect cross-reacting antibodies.
c. Rickettsial antibodies should be tested using the fluorescent treponemal antibody absorption (FTA-ABS) test, not the Weil-Felix test.
d. No discrepancy is present. Rickettsial an-tibodies do not agglutinate with Proteus antigens.


A
The Weil-Felix test is an older method and is not as sensitive as some of the newer tests; there-fore, infections should be retested to ensure an accurate result.

Biology & Microbiology

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