Which clients would the nurse consider high risk for adverse drug effects related to inefficient blood–brain barrier?
1. Older adult taking benzodiazepines for anxiety
2. Older adult with a current history of seizures
3. Older adult with a history of difficulty sleeping
4. Older adult taking high doses of antibiotics for pneumonia
5. Older adult with a history of emphysema
Correct Answer: 1,2,3
Rationale 1: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the blood–brain barrier in higher concentrations, resulting in adverse effects.
Rationale 2: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the blood–brain barrier in higher concentrations, resulting in adverse effects.
Rationale 3: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the blood–brain barrier in higher concentrations, resulting in adverse effects.
Rationale 4: Antibiotics for pneumonia do not cross the blood–brain barrier.
Rationale 5: Drugs used for emphysema would not cross the blood–brain barrier.
Global Rationale: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the blood–brain barrier in higher concentrations, resulting in adverse effects. Antibiotics for pneumonia do not cross the blood–brain barrier. Drugs used for emphysema would not cross the blood–brain barrier.
You might also like to view...
Expected physical changes associated with older adults include:
a. shiny buccal mucosa. b. shorter teeth. c. wetter nasal mucosa. d. bristly hairs in the vestibule.
The following medication order has been written for a client: Indomethacin 15 mg oral suspension PO q 6 hours. The nurse has the following medication available: 25 mg/5 mL
How many mL of the medication will the nurse provide to the client? Round to the nearest whole number.
The conversion factor for micrograms to milligrams is 1 mcg:100 mg
Indicate whether the statement is true or false
You have recently returned from a medical missions trip to sub-Saharan Africa, where you learned a great deal about malaria. You decide to use some of the same questions and maneuvers in your “routine” when examining patients in the midwestern United States. You are disappointed to find that despite getting some positive answers and findings, on further workup, none of your patients has
malaria except one, who recently emigrated from Ghana. How should you next approach these questions and maneuvers? A) Continue asking these questions in a more selective way. B) Stop asking these questions, because they are low yield. C) Question the validity of the questions. D) Ask these questions of all your patients.