Identify a difference between nondepolarizing blockers and depolarizing blockers.
A. The nondepolarizing blockers combine with the Nm receptors, whereas the depolarizing blockers do not.
B. The nondepolarizing blockers inhibit cholinergic activity by attaching themselves to the synaptic vesicles containing ACH and preventing ACH from being released into the synaptic cleft, whereas depolarizing blockers inhibit cholinergic activity by occupying the nicotinic-muscle sites so that acetylcholine (ACH) cannot bind with the receptors.
C. The nondepolarizing blockers stimulate the nicotinic-muscle (Nm) receptors, whereas the depolarizing blockers do not.
D. The nondepolarizing blockers inhibit cholinergic activity by occupying the nicotinic-muscle sites so that acetylcholine (ACH) cannot bind with the receptors, whereas depolarizing blockers inhibit cholinergic activity by altering the Nm receptors so that they cannot respond to ACH stimulation.
Answer: D
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