The nurse is teaching a prenatal class for mothers with a past history of drug abuse. Which factor would the nurse need to emphasize about the first trimester of pregnancy?

1. There is very little chance of the fetus being affected by teratogens during this phase.
2. Teratogenic agents taken during this phase can lead to structural malformation and spontaneous abortion.
3. This is the preconceptional period of the pregnancy.
4. Teratogenic agents during this phase do not cause severe malformations in the fetus.


Correct Answer: 2
Rationale 1: This is the phase when teratogens have the greatest effect on the embryo.
Rationale 2: In this phase, all the body systems form.
Rationale 3: This is the embryonic period.
Rationale 4: This is the phase when teratogens have the greatest effect on the embryo resulting in possible severe malformations.
Global Rationale: In the first trimester of pregnancy, all the body systems form and this is the time when teratogens have the greatest effect on the embryo and can result in severe malformations. The first trimester is known as the embryonic phase.

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