A woman who is a carrier for which of the following diseases possesses the greatest likelihood of passing the disease to her future children when heterozygous pairing exists?
A) Phenylketonuria (PKU)
B) Tay-Sachs disease
C) Neurofibromatosis
D) Cystic fibrosis
Ans: C
Feedback:
Neurofibromatosis is an autosomal dominant genetic disorder with a consequent 50% chance of passing the disease to offspring. Tay-Sachs disease, PKU, and cystic fibrosis are autosomal recessive disorders and are manifested only when both members of the gene pair are affected.
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