A patient has received an initial dose of glatiramer acetate (Copaxone) for relapsing-remitting multiple sclerosis. The nurse notes that the patient appears flushed and anxious and has urticaria
The patient reports palpitations, chest pain, and a feeling of laryngeal constriction. What will the nurse do?
a. Obtain an order for epinephrine to treat a hypersensitivity reaction.
b. Prepare to provide cardiorespiratory support.
c. Report a possible cardiotoxic episode to the provider.
d. Stay with the patient until this self-limiting episode passes.
ANS: D
About 10% of patients taking glatiramer acetate experience a self-limited postinjection reaction characterized by flushing, palpitations, severe chest pain, anxiety, laryngeal constriction, and urticaria; the episode usually lasts 15 to 20 minutes. No treatment is required, but the nurse should stay with the patient to help alleviate anxiety associated with this reaction. Epinephrine is not indicated. Cardiorespiratory support is not necessary. This does not represent a cardiotoxic reaction.
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