Which patient would require careful assessment for toxic effects of lithium? The individual taking lithium and
a. hydrochlorothiazide (HCTZ).
b. lorazepam (Ativan).
c. clozapine (Clozaril).
d. oxazepam (Serax).
A
Hydrochlorothiazide is a diuretic used to treat hypertension. The diuretic effect would increase serum concentrations of lithium, potentially producing toxicity. Benzodiazepine and antipsychotic drugs are commonly used concurrently with lithium to control mania.
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