Penny has a headache, so she takes a 250-mg tablet of aspirin to alleviate the pain. After a while, she begins to feel nauseous. What is the reason for this occurrence?
A. A headache is not an indication for the use of aspirin.
B. Aspirin causes a buildup of COX-2 inhibitors in the body.
C. A dose of 250 mg is double the recommended dose for an adult.
D. Aspirin is known to irritate the stomach mucosal lining.
Answer: D
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