There is some evidence that venlafaxine and duloxetine may be more effective than the SSRIs in the management of depression, especially when associated with:

a. physical pain
b. insomnia
c. psychosis
d. mania


A
Venlafaxine and duloxetine may be more effective than the SSRIs in the management of depression, especially when associated with physical pain. Venlafaxine, an agent that has an effect on both serotonin and norepinephrine brain pathways, is similar in side effects to SSRIs; however, it may elevate blood pressure in some persons.

Nursing

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