A client with breast cancer is receiving 5-Fluorouracil (5-FU). Based on knowledge of this medication and its anticipated adverse effects or side effects, which nursing action should the nurse perform?
1. Monitor ECG
2. Assess lung sounds
3. Test stool for occult blood
4. Encourage daily fluid intake of 2–3 liters
3. Test stool for occult blood
Rationale:
The possible adverse effects or side effects associated with 5-FU are stomatitis, alopecia, nausea and vomiting, gastritis, enteritis, diarrhea, anemia, leucopenia, and thrombocytopenia. Assessing for bleeding by checking stool for occult blood is recommended in this client. Monitoring the ECG is recommended in clients receiving antitumor antibiotics. Assessing lung sounds is recommended in clients receiving alkylating agents, due to the potential for developing pulmonary fibrosis. Encouraging a daily fluid intake of 2–3 liters is recommended also for clients receiving alkylating agents because they could potentially develop renal failure.
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