Although the use of hormone replacement therapy (HRT) for perimenopausal symptoms is still under investigation, the results of a large-scale study halted in 2002 reported which of the following findings related to HRT? (Select all that apply.)
a. A reduction in total fractures
b. A decrease in strokes
c. A decrease in colorectal cancer
d. An increase in thromboembolism
e. An increase in heart attacks
f. A decrease in breast cancer
ANS: A, C, D, E
Research on HRT has shown a 26% increase in breast cancer, a 41% increase in strokes, a 29% increase in heart attacks, doubling of venous thromboembolism rates, and an overall 22% increase in cardiovascular disease. Positive findings with HRT included a one-third reduction in hip fractures, a 24% reduction in total fractures, and a 37% decrease in colorectal cancer.
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A) True B) False