A 28-year-old woman complained of blurry vision, tingling in her fingers, and weakness in both legs. Magnetic resonance imaging revealed numerous plaques in the cerebral white matter. The cerebrospinal fluid analysis most likely will show
A. numerous neutrophils
B. eosinophilia
C. reduced glucose concentration
D. oligoclonal bands of immunoglobulins
E. xanthochromia
D
This woman most likely has multiple sclerosis, a disease characterized by the appearance of oligoclonal immunoglobulin bands. Neutrophils are a feature of bacterial meningitis. Eosinophils are seen in parasitic infections. The cerebrospinal fluid in multiple myeloma usually contains an increased number of lymphocytes. Xanthochromia, a yellowish discoloration of the cerebrospinal fluid, is usually a consequence of bleeding and bilirubin release from damaged erythrocytes.
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