What are monoclonal antibodies? How are they produced, and what are some of their clinical uses?

What will be an ideal response


Monoclonal antibodies are pure antibody preparations that exhibit specificity for a single antigenic determinant. They are produced from the progeny of a single B cell hybridoma "clone," prepared by injecting a specific antigen into a lab animal and then harvesting sensitized B cells from its spleen. The cells are mixed with myeloma cells and incubated, and the resulting hybridoma cells (B cells fused with myeloma cells) produce the monoclonal antibody. They are used for the diagnosis of pregnancy, certain sexually transmitted diseases, hepatitis, rabies, and for other purposes.

Anatomy & Physiology

You might also like to view...

The condition where fluid compresses the heart and limits its ability to contract is called ________

A) cardiac tamponade B) myocardial infarction C) pericarditis D) angina pectoris

Anatomy & Physiology

Match the term with the appropriate description.A. Dead tissueB. A floating clotC. Sudden decreased blood supply to a part of the brainD. A stationary clotE. A localized area of dead cells resulting from ischemiaInfarct

Fill in the blank(s) with the appropriate word(s).

Anatomy & Physiology

A person who sustains damage to the spinal cord at the level of the lumbar plexus will suffer from ________.

Fill in the blank(s) with the appropriate word(s).

Anatomy & Physiology

The ________ of the eye contains the pigmented cells that are responsible for eye color

A) lens B) cornea C) cones D) iris

Anatomy & Physiology