Parents of a child with anemia of unknown cause learn that their child will be tested for sickle cell anemia. The parents ask the nurse to explain why after having a sickle solubility test the child is now going to have a hemoglobin electrophoresis
Which of the following explanations by the nurse would be most accurate? a. The physician has to verify the results of the first test and doesn't like to base a diagnosis on just one test.
b. The solubility has to do with the sickle cell and the electrophoresis with the severity of the anemia.
c. The solubility test has to do with what solutions will dissolve a sickle cell and the electrophoresis with determining the electrical charge.
d. The solubility test is to detect the presence of hemoglobin S(Hb S), while the hemoglobin electrophoresis is to determine the amount of Hb S in the blood.
D
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A Incorrect. Explaining why the solubility test is followed by a hemoglobin electrophoresis test, the most accurate statement is not that the physician needs two tests to verify the results.
B Incorrect. Explaining why the solubility test is followed by a hemoglobin electrophoresis test, the most accurate statement is not that hemoglobin electrophoresis reveals the severity of the anemia.
C Incorrect. Explaining why the solubility test is followed by a hemoglobin electrophoresis test, the most accurate statement is not that the solubility test has to do with what solutions will dissolve a sickle cell and the electrophoresis with determining the electrical charge.
D Correct. Testing would begin with a sickle solubility test in order to confirm the presence of Hb S in the blood. If this test is positive, hemoglobin electrophoresis would then be conducted to determine the amount of Hb S in the blood. The results of this test can then be used to differentiate SCA from other types of sickle disease.
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