A solitary cold nodule on Radioactive Iodine (RAI) uptake on a thyroid scan is suspicious for:
A. Hyperthyroidism
B. Myxedema
C. Trigeminal neuralgia
D. Thyroid Cancer
ANS: D
Hyperthyroidism does not necessarily coincide with a thyroid nodule. Myxedema is a tissue swelling of the face and body due to hypothyroidism. Trigeminal neuralgia causes paroxysms of pain on one side of the face. Thyroid cancer presents as a solitary cold nodule on a thyroid ultrasound. Predisposing factors include female gender, positive family history, and history of radiation exposure to the head, face, or neck.
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