Compare the differences in the activation of complement that can lead to intravascular hemolysis or extravascular hemolysis
What will be an ideal response?
Answer: In intravascular hemolysis the antibody (usually an IgM) is able to fix complement and cause activation through the MAC. Once C9 has been fixed, the lysis of the cell begins, resulting in intravascular hemolysis. IgG antibodies are not efficient complement fixers, and complement often is fixed only through the C3 component. C3a is released into the plasma and C3b remains on the cell. There are receptors for C3b on splenic and liver macrophages so that cells are removed extravascularly.
You might also like to view...
Because of the possibility of extended time in the field, for rescue patients, you must be prepared to provide:
a. ongoing assessment. c. treatment protocols. b. stabilization techniques. d. psychological support.
A patient with high blood pressure takes a medication to slow his heart rate, thereby lowering his blood pressure. The EMT would recognize this action as impacting:
A) Preload B) Afterload C) Systemic vascular resistance D) Cardiac output
Hypothermia is not a common complication of drowning.
Answer the following statement true (T) or false (F)
When a definition or disease requires more than one line in the ICD-10-CM index, that text is printed on the next line and indented _____ spaces
a. 2 b. 4 c. 5 d. 6