From where are additional platelets first derived when the circulating count decreases?
a. Bone marrow
b. Stem cells
c. Cells marginated on vessel endothelial cells
d. The 30% of mature cells stored in the spleen
ANS: D
When the circulating platelet count decreases, platelets are first derived from those sequestered or stored in the spleen (normally one third of those available).
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