The nurse administers a drug with a half-life of 12 hours. To maintain a steady state of the drug, the nurse recognizes that the medication will need to be administered every:
1. 4 hours.
2. 6 hours.
3. 12 hours.
4. 24 hours.
Answer: 3
1. After 12 hours, 50% of the drug will have been metabolized. Four hours would be too soon to provide another dose of this medication.
2. After 12 hours, 50% of the drug will have been metabolized. Six hours would be too soon to provide another dose of this medication.
3. After 12 hours, 50% of the drug will have been metabolized, and the drug will need to be given again in order to maintain a steady blood level of drug.
4. After 12 hours, 50% of the drug will have been metabolized. Another dose should be provided before 24 hours.
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